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Description
This may explain why it reduces discomfort in wound models in addition to accelerating repair
Reprinted with permission from [31]

This process was abrogated by the glycolysis inhibitor 2-deoxy-D-glucose (2-DG), confirming the central role of metabolic reprogramming in immune training (148)
Its activity depends on the presence of selenium, specifically in the form of selenocysteine located at the enzymes active site [80]
validation, M.R.-I., S.S
SHANK3 mutations are likely to cause mitochondrial dysfunction in PMS because six mitochondrial genes, including NADH dehydrogenase 1 alpha subcomplex subunit 6 (NDUFA6 ), cytochrome c oxidase assembly ( SCO2 ), tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase ( TRMU ), thymidine phosphorylase ( TYMP ), carnitine palmitoyltransferase 1B ( CPT1B ), and aconitase 2 ( ACO2 ), are adjacent to SHANK3 in the 22q13.3 region [339]