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S-Nitrosylation of 1-antitrypsin triggers macrophages toward inflammatory phenotype and enhances intra-cellular bacteria elimination

In a model of sepsis-induced neuroinflammation, hydrogen has been shown to decrease the polarization of M1-type microglia while increasing the polarization of M2-type microglia through the modulation of mTOR-autophagy-dependent pathways (Zhuang et al., 2020)

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Isocitrate lyase (ICL) inhibitors ICL plays a crucial role in mycobacterial glyoxylate and methyl isocitrate cycles, which are essential for M.tb survival, virulence [100], and antibiotic tolerance [101]

In Vitro Cell Dev Biol Plant 48:113119 Shao HB, Chu LY, Lu ZH, Kang CM (2008) Primary antioxidant free radical scavenging and redox signalling pathways in higher plant cells