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Astrocytes are best suited for this role due to their ability to store glucose as glycogen and their simultaneous connection to many neurons [102]

This adaptation renders the cancer cells to survive in relatively high oxidative stress condition compared to normal cells, as well as protects cancer cells from toxic action of chemotherapeutic agents

For the skin penetration study, the dorsal skin of each mouse was cleaned using an alcohol pad, and 14 mg of cream containing 0.2% FITC-GHK, FITC-RGD-GHK, or FITC-sOtx2-GHK peptides were smeared uniformly on the skin (1 cm 2 )

In addition, activation of Janus kinase-2 (JAK2) and NF-B resulted in transcription of NF-B-dependent neuroprotective genes

Glutamine metabolism Glutamine is the most abundant and widely used amino acid in the body [127, 128]

Amino acid metabolism detection employs two main methodologies: biochemical analyses and advanced metabolomics