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Furthermore, comparing Prdx Km for H 2 O 2 with that of GPx and catalase exceeding even the millimolar range [180] suggests that the role of Prdx is rather as a sensor of H 2 O 2 [178] than oxidative stress condition reversal

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In agreement with published data, these cells were hardly sensitive to FA when compared to the isogenic cell line expressing a wild type copy of FANCD2 (PD20-wtD2) 39 (Fig

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