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A study of 20 cases

How to prepare It is important to consult with your physician before considering Vitamin B12 injections, as they should not be used if you have Lebers disease (because of an increased risk for damage to the optic nerve) or any deficiencies or allergies, especially to cobalt

Haptocorrin (R-binder) is a glycoprotein released in saliva, bile, and pancreatic fluid and plays an essential role in the protection of B12 from the acidic environment of the stomach [12]

Ive maintained my exercise routine, including 2.5M runs a few times a week and it hasnt seemed to cause any issues with these, though I was a little worried about it

If there is, this indicates that youve hit a blood vessel very unlikely when injecting into the stomach but this step is a recommended precaution

As for transcobalamin II deficiency, an observational case series of 30 patients revealed that IM administration of 1 mg of OH-Cbl or CN-Cbl weekly for a lifetime appears to be a suitable treatment regimen (Trakadis et al., 2014)