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doi: 10.1021/ac902227z

Blood 108(11):2532, 2006

In cancer cells, GSH and enzymes of the mercapturic acid pathway play a role in resistance to many chemotherapeutic drugs

Platelet inflammatory response to stress

Key regulatory axesincluding HIF-1, HHIP-PKM2, PTGES-AKT-HIF-1, and lactate/LDH-A (LDH5)-TGF-interact to collectively promote enhanced glycolysis and diminished oxidative metabolism, sustaining the pathological phenotype of the disease (8082)

Lenzi A, Sgr P, Salacone P, Paoli D, Gilio B, Lombardo F, et al
