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Description
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81 , 92 In primary cells from BM aspirates of MM cells, isatuximabinduced apoptosis without any addition of external crosslinking agents and independent of effector cells

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In a Phase I crossover study involving healthy volunteers (NCT04384666), the pharmacokinetic profile of a single dose of LY03003 (28 mg) injected intramuscularly was compared with a 7-day regimen of Neupro, indicating that the injectable system could provide sustained drug release over an extended period 140
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