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Efficacy of Folic Acid Therapy on the Progression of Chronic Kidney Disease: The Renal Substudy of the China Stroke Primary Prevention Trial

Epithalon , thymalin , and certain nootropic peptides are particularly sensitive

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It upregulates the expression of early growth response protein 1 (EGR-1), a transcription factor that controls over 30 downstream genes involved in cytokine production, growth factor signaling, and extracellular matrix remodeling