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Blood Glucose Evaluation Blood glucose level in the control animals was relatively stable throughout the duration of the study while an increase in blood glucose level was observed in the diabetic groups (DU, DMg250 and DI) on day 0 (356 38.7 mg/dl, 340 56.2 mg/dl, 252 35.8 mg/dl) after the establishment of diabetes mellitus (fig

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Moreover, the preservation of cell integrity via autophagy is essential for preventing neurodegeneration in dopaminergic neurons through apoptosis, involving a regulatory mechanism linked to the AKT/mTOR pathway (Zhu et al., 2024)

Apart from this, several other factors like iodine deficiency, removal of the thyroid gland through surgery, radiation therapy, certain medicines, etc