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An increased osmolarity of the tear film triggers a conformational change in these TRPV1 channels, leading to their opening

Histological studies demonstrate disorganised collagen fibres and increased matrix metalloproteinase activity within tendons, changes associated with oxidative stress and disrupted extracellular-matrix turnover (83)

Body composition: Some studies have reported slight reductions in fat mass, though results remain inconsistent across different populations

(Xu et al., 2015b)

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10.3390/antiox9100943 126 JacobsH.PetersR.Den HartogG
