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It has been established that heat stress in poultry can have a significant impact on the systemic immune response, making birds more susceptible to pathogens, particularly through the gastrointestinal tract (Brugaletta et al., 2022)

The balance between benefits and risks/burdens (i.e., AEs) was considered

Author Contributions Ruimiao Qian, Hui Fu, and Jun Ge framed the synthesis

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While the optimal sampling strategy is unknown, biopsies should be obtained from multiple liver lobes, as we have recognized wide ranges of severity between different lobes in the same cat

Immunomodulation of human mesenchymal stem/stromal cells in intervertebral disc degeneration: insights from a proinflammatory/degenerative Ex Vivo model