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The ferroptosis inducers such as glutamate, erastin are able to drain GSH and inactivate the enzymatic activity of GPX4 via blocking the import of cystine by the cystine/glutamate antiporter (system X c ) [27, 28] (Fig

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The results of the above described pharmacological investigations demonstrate the advantageous activity of the salts of the BPC peptides in protecting organisms against stress and diseases and, in general, normalizing the organic functions

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[DOI] [PMC free article] [PubMed] [Google Scholar] 130.Spadaro D., Yun B.W., Spoel S.H., Chu C.C., Wang Y.Q., Loake G.J