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Being an antidepressant belonging to the class of serotonin-2 antagonist/reuptake inhibitors, TRZ is a potent and selective postsynaptic 5-HT 2A antagonist and a moderately potent serotonin reuptake inhibitor, with high affinity for 5-HT 2A receptors and moderate affinity for 5-HT 1A and 5-HT 2C receptors [14,15,16]

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The sustained levels may also increase the likelihood of certain side effects, particularly joint stiffness and water retention

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Tirzepatide vs semaglutide thigh injections Both medications are subcutaneous injections targeting the same tissue layer