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In all SURPASS programs, tirzepatide demonstrated a much greater HbA1c-lowering impact than placebo or active comparators, such as basal insulin and GLP1RAs [83, 86]

Anxiety and mood changes can occur, particularly during rapid weight loss phases

Thus, the investment case for the two leading manufacturers of GLP-1s does look compelling

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Semaglutide (GLP-1 agonist) helps patients lose 1015% of total body weight , making it one of the nations leading medical weight loss options

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