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Dlatego Semaglutyd mona stosowa w leczeniu chorb neurologicznych, takich jak choroba Parkinsona, choroba Alzheimera i stwardnienie zanikowe boczne

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Additionally, selective deletion of Gipr in brown adipose tissue significantly increases both fasting (overnight) and fed (1h re-feed) TG levels of high-fat fed mice ( Gipr BAT / mice fed a high-fat diet for 810 weeks housed at room temperature reveal significantly increased TG excursion, an effect lost upon 28 weeks of high-fat feeding (Kim et al., 2007a) mediated by resistin (Kim et al., 2007b) and in human adipocytes by increasing TORC2 and phospho-CREB nuclear localization to bind to the CRE-II promoter region (Kim et al., 2010)

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This is also reflected in expression levels of a number of different genes at the level of visceral adipose tissue (Fig