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Combining semaglutide and testosterone replacement therapy may benefit weight management and sexual function in men, but research is limited.

Oral semaglutide works by acting as a GLP-1 receptor agonist, helping to regulate appetite and reduce food intake

The positive impact of GLP-1RA therapy on lipids is an important contributor to these outcomes.

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Sodium butyrate reduces high-fat diet-induced non-alcoholic steatohepatitis through upregulation of hepatic GLP-1R expression
