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Weekly or biweekly weigh-ins are generally recommended rather than daily measurements, as day-to-day fluctuations due to fluid shifts, dietary sodium intake, and hormonal changes can obscure the underlying trend

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The retrospective design introduces potential for unmeasured confounders, and the lack of standardised ICP measurements across centers may impact the generalizability of our findings

But research consistently shows that regular physical activity improves fatigue, even when the fatigue is medication-related

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