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These considerations can significantly impact your ability to start and continue treatment

Amplifies beta-cell insulin secretion through pathways distinct from GLP-1R, modulates adipose tissue lipid handling, and appears to reduce the GI adverse-event burden associated with isolated GLP-1R agonism
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GLP-1 receptors are found in parts of the brain that regulate appetite and feelings of fullness

doi: 10.1016/j.bbrc.2013.12.049

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