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Description
TREK-1 regulation by nitric oxide and cGMP-dependent protein kinase

This is especially useful after meals or when the taste feels stronger during the day

, Williams, G

The Specialist Pharmacy Service (SPS) and NHS practice guidance advise that when a GLP-1 receptor agonist is introduced, any DPP-4 inhibitor should generally be discontinued due to the mechanistic overlap and lack of additive benefit

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May slow gastric emptying and reduce post-meal blood glucose spikes, similar to GLP-1 effects
