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Description
GLP-1 receptor distribution and function by tissue The brain: appetite, satiety, and reward The central nervous system is where much of the modern interest in GLP-1 lives, because the brain is where appetite is controlled

Glucagon-like peptide-1 receptor agonists (GLP-1 RAs), initially developed for the treatment of type 2 diabetes and obesity, may modulate pathways associated with the hallmarks of aging

Expert Rev Clin Pharmacol
Studies have shown that liraglutide reduces the numbers of A and dense core plaques in the cortex by 4050% (McClean et al., 2011)

The areas that show change first depend on your body fat distribution pattern
BLOOD PRESSURE SGLT2 inhibitors decrease systolic BP by approximately 3-6 mmHg and diastolic BP by approximately 2-3 mmHg (22,139)