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Lost in translation: the valley of death across preclinical and clinical divide identification of problems and overcoming obstacles

GLP-1 therapies have dramatically expanded that scale

Se muestra eficaz en la reduccin de grasa heptica y mejora de MASH hasta en el 62% de los participantes tratados con inyeccin semanal de 4,8mg
Tirzepatide is a dual GIP/GLP-1 receptor agonist, meaning it targets two incretin pathways simultaneously

Singh G., Krauthamer M., and BjalmeEvans M., Wegovy (Semaglutide): A New Weight Loss Drug for Chronic Weight Management, Journal of Investigative Medicine 70 (2022): 513

10.1007/s40279-021-01605-8 [DOI] [PubMed] [Google Scholar] 29