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Only specific oral formulations with absorption enhancers were tested and approved

Concurrently, we observed upregulation of several key genes involved in the HBP, which enhanced OGT expression and functionality, while OGlcNAcase (OGA) levels remained unchanged (Figure 4F)

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With the goal of enhancing patient outcomes and enabling practitioners to overcome physician supply shortages, there is an urgent need to explore new pharmacologic therapies that target mechanisms of neuro-ophthalmic degeneration

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