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The elegance of this approach is worth noting

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PubMed Frias, J.P., Davies, M.J., Rosenstock, J., Prez Manghi, F.C., Fernndez Land, L., Bergman, B.K., et al

reported in the early 90 s that GLP-1 interacted with exendin receptors on dispersed acini from guinea pig pancreas 22,23 , and these concerns were increased with the results from the LEADER trial showing a numerically greater, although statistically not significant, number of cases of pancreatic cancer in the liraglutide arm compared to the placebo 20

Tirzepatide shows superior outcomes (21-22% weight loss) compared to semaglutide (13-17% weight loss) in head-to-head trials

Rehydration is crucial in managing DKA to maintain fluid balance, improve tissue perfusion, and facilitate the excretion of excess glucose and ketones