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doi: 10.1056/NEJMoa2313917

"Despite these promising findings, significant caveats remain, including side effects like nausea, a curb in appetite, and weight loss." The first few trials conducted on rats and mice that were addicted to nicotine, alcohol, and other stimulants showed effective reduction in craving and relapse when treated with GLP-1 therapy

Additionally, this research which included data from tens of thousands of patients, found that the drugs seem to be slightly more effective for women than men

Accordingly, we suggest that communication should focus on uncertainty managementneither exaggerating teratogenic risks nor downplaying the metabolic and pregnancy costs of post-discontinuation rebound

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