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We often focus on the main benefits or side effects of new medications, but awareness of less obvious impacts (such as those on oral health) allows each of us to take practical steps to protect our well-being

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Central pontine myelinolysis Altered level of consciousness, including coma Locked-in syndrome Impaired cranial nerve function: dysarthria, dysphagia , and diplopia Worsening quadriparesis (initially flaccid, later spastic) Extrapontine myelinolysis: parkinsonism (tremor, rigidity), dystonia, chorea or choreoathetosis, myoclonus, opsoclonus, ataxia, gait disorders Other general symptoms: seizures, encephalopathy, catatonia, mutism, frontal release signs, depression Diagnostics: Imaging may only show signs of ODS days to weeks after the onset of symptoms

doi:10.1111/jce.12066 4

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