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Access the complete GLP-1 Pipeline Update table for February 2026

Data extracted from the selected studies included: study design, sample size, participant demographics, diagnostic criteria, intervention details, comparator, duration of treatment, outcome measures, key efficacy and safety results, and limitations

Archives of Medical Science

As for safety, the mid-stage trial found Ziihera to be well-tolerated, with only two patients discontinuing treatment due to toxicities
The incidence of vomiting was 13% with dulaglutide at 1.5 mg, 8% at 0.75 mg, and 2% with sitagliptin

Fat mass decreases substantially, with visceral fat (the dangerous fat surrounding internal organs) dropping proportionally more than subcutaneous fat
