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The GIPR rs1800437 variant affects glucose-dependent insulinotropic peptide signaling, which overlaps with satiety regulation

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The theory explains why depressed patients have atrophied limbic brain regions on imaging studies and low hippocampal BDNF postmortem (Duman & Li, 2012)

[DOI] [PMC free article] [PubMed] [Google Scholar] 72.Karagiannis T., Tsapas A., Athanasiadou E., Avgerinos I., Liakos A., Matthews D.R., Bekiari E

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