retatrutide weight loss trial results Results:Trial Data and FDA Status Retatrutide, a TRIPLE agonist (GLP1,

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GLP-1 drugs are a class of medicines originally developed to treat type 2 diabetes

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The initial decrease in body weight is the result of two major effects of SGLT2 inhibition: caloric loss due to glucose excretion (a process also called calorie restriction mimicry) and loss of body water due to osmotic diuresis

Therefore, this review aims to synthesize current evidence on the use of GLP-1 RAs in women planning pregnancy, evaluate emerging safety data, and discuss practical clinical approaches for managing these patients