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See how RYBELSUS performed in the PIONEER 3 Trial

Summary SGLT2-i exert more consistent BP-lowering effects than GLP-1RA, largely due to their diuretic-like action
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Synjardy (empagliflozin/metformin) is a brand-name prescription drug thats used to treat type 2 diabetes

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Semaglutide restored GSK3-Drp1 signalling, maintained mitochondrial membrane potential, and decreased mitochondrial fragmentation in primary cardiomyocytes via GLP-1R activation