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In adipose tissue, GIPR promotes lipid storage and reduces lipolysis, contributing to energy balance

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In rats injected with 6-OHDA or lipopolysaccharide (LPS), nigrostriatal dopamine levels and the l-DOPA synthesizing capabilities of these cells were markedly diminished, in line with reduced levels of TH-positive neurons
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Or they focus exclusively on cardio, which doesn't provide a strong muscle-preservation signal to the body