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The mighty glucagon-like peptide 1 receptor agonist from Novo Nordisk A/S was already approved for those age 12 and older who are obese and for some overweight adults with weight-related problems.
A notable pattern also emerged around other reward-seeking behaviours: a significant proportion of participants noticed reduced interest in alcohol, impulsive purchasing, and other dopamine-driven activities
Mechanistically, we identify a subset of Glp1r -expressing neurons in the dorsal vagal complex that, upon semaglutide treatment, regulate genes involved in anti-inflammatory signaling
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