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If GI side effects persist beyond the adjustment period or are severe enough to significantly impact quality of life, dose adjustment may be warranted

Hemorrhoids Hemorrhoids are swollen blood vessels in the rectum that can bleed, especially with: Constipation Increased pressure during bowel movements These are common and generally non-serious causes of blood in stool

Sympathetic nervous system effects may contribute to heart rate changes

Postbiotics, including heat-inactivated bacteria, have demonstrated real biological activity in multiple studies