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Notably, activation of GLP-1R + neurons in the hypothalamus and brainstem reduces food intake and promotes weight loss

They can also help you navigate social situations, dining out, and manage cravings that may arise along the way

The researchers found no association between the use of GLP-1 RAs and thyroid cancer (weighted HR [wHR] 0.98, 95% CI 0.621.53) compared to that of SGLT2 inhibitors

For people with commercial insurance that doesnt cover weight loss medication, Eli Lilly offers Zepbound pens for $650 per month

Whereas the GLP-1 drug Ozempic is injected once weekly at 2 mg, Rybelsus is taken daily and requires a minimum dose of 14 mg to achieve comparable glycemic effects

But the picture is not uniformly positive