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Expect microencapsulation, pH-triggered release, and pairing with protein or viscous fibres
Whether adding cagrilintide preserves more lean mass than retatrutide alone or whether the added satiety drives more lean-mass loss by reducing protein intake further is unknown

GLP-1s increased the release of insulin but had an extremely short half-life (one to two minutes), making them highly unfavorable as a treatment for diabetes

Muskiet MHA, Wheeler DC, Heerspink HJL

doi: 10.1136/bmjopen-2022-061476

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