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The team included BBRF Scientific Council member Nora Volkow, M.D., a leading expert on addiction who is director of the NIHs National Institute on Drug Abuse (NIDA)

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Fasting activation of AgRP neurons requires NMDA receptors and involves spinogenesis and increased excitatory tone

[DOI] [PubMed] [Google Scholar] 190.Tronieri J.S., Wadden T.A., Walsh O., Berkowitz R.I., Alamuddin N., Gruber K., Leonard S., Bakizada Z.M., Chao A.M

It sounds like, you know, the insulin metaphor I think is a little challenging because it'll literally kill you, right

Circulation 145(18):e895e1032 Bozkurt B, Coats AJS, Tsutsui H, Abdelhamid CM, Adamopoulos S, Albert N, Anker SD, Atherton J, Bhm M, Butler J et al (2021) Universal definition and classification of heart failure: a report of the Heart Failure Society of America, Heart Failure Association of the European Society of Cardiology, Japanese Heart Failure Society and Writing Committee of the Universal Definition of Heart Failure: Endorsed by the Canadian Heart Failure Society, Heart Failure Association of India, Cardiac Society of Australia and New Zealand, and Chinese Heart Failure Association