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88,89 For example, PVN plays a significant role in elevating sympathetic-driven hypertension, while some studies have demonstrated that disequilibrium of GABA and AVP neuron transduction in PVN may play a role in the pathogenesis of hypertension

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The FLOW study particularly indicated that semaglutide decreased the progression to end-stage renal disease by 24% in individuals with diabetic kidney disease (Rossing et al