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"Of all my medications, it's the only one not subsidised," she said, adding that she hopes GLP-1 medications will eventually be subsidised for patients using them to manage chronic, life-threatening conditions

J Neurosci

In non-diabetic mice, GLP-1 infusion increased GFR by reducing preglomerular resistance [20], an observation that could potentially explain the physiological increase in GFR observed in the postprandial compared to the fasting state, although human studies infusing GLP-1 peptide could not replicate this observation [21]

Future efforts should focus on: Validating composite diagnostic algorithms that integrate clinical, imaging, and molecular data

Then, Novo Nordisk worked on a new generation GLP-1 RA, semaglutide, and commercialized it successfully

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