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The 10 mg dose of tirzepatide showed greater weight reduction versus semaglutide 1 mg by -1.8 mmHg (-3.4 to -0.1) while the 15 mg dose of tirzepatide reduced an additional -3 mmHg (-4.6 to -1.3) compared to semaglutide [65]

By Application, Type 2 Diabetes Mellitus dominated the GLP-1 Market in 2025

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95% CI, 0.73-1.90) ( The AMPLITUDE-O trial, which studied Efpeglenatide versus placebo with a mean follow-up of 1.81 years, demonstrated a significant 27% reduction in MACE

Tissue-specific expression of unique mRNAs that encode proglucagon-derived peptides or exendin 4 in the lizard