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In one study that aimed to identify the specific neuronal site affected by GLP-1R agonist interaction with GLP-1R, the gene encoding GLP-1R in the central nervous system (CNS) or peripheral nervous system was deleted45)
doi: 10.2337/db22-719-P
doi: 10.1016/j.ebiom.2016.03.034 20 DhanvantariSSeidahNGBrubakerPL
How do we decide from a clinical perspective where we start with each patient
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