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Nonclinical studies suggest the addition of GIP may further contribute to the regulation of food intake

Patients with severe gastrointestinal disease should avoid tirzepatide

Few drugs have surpassed the $20 billion threshold

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On average, volunteers in the retatrutide clinical trial who received the study drug rather than a placebo lost an average of 70.3 pounds over about a year-and-a-half, with more than 45% of participants losing more than 30% of their body weight