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22 However, the fact that the magnitude and speed of hemoglobin A1c reduction with treatment were identified as risk factors for progression suggests it could be another example of the well-established early worsening phenomenon first observed in type 1 diabetic patients intensively treated with insulin in the Oslo Study, Kroc Collaborative Study and Diabetes Control and Complications Trial

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In a mouse model of osteoarthritis induced by destabilization of the medial meniscus, glycoursodeoxycholic acid was found to mitigate disease progression, an effect associated with an increase in intestinal L cell numbers (87)

Influences of dietary added sugar consumption on striatal food-cue reactivity and postprandial GLP-1 response

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