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When the blood glucose level is high (a condition known as hyperglycemia), it can induce harmful changes in the brain, such as inflammation, oxidative stress, and damage to brain cells

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I think this truly gives us a very powerful tool to treat obesity as a disease.

In addition, it should be noted that RCTs usually do not reflect a population of real-world patients with multiple comorbidities, medication burdens and socioeconomic factors affecting their adherence

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