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It cannot yet be legally prescribed, and Lilly continues to compile comprehensive efficacy and safety data ahead of any regulatory submissions

For example, specific variants in the GLP1R gene can affect receptor sensitivity, while FTO rs9939609 variants relate to appetite regulation and energy metabolism

Insights from Research: Research, such as a comprehensive review in the American Journal of Physiology-Endocrinology and Metabolism , underscores the potential of GLP-1 in addressing obesity-related concerns

Available at: Gorgojo-Martnez JJ, Mezquita-Raya P, Carretero-Gmez J, et al

The mechanistic rationale is described in the phase 2 publications by Rosenstock et al

Diet: Unhealthy eating habits, including a diet high in processed foods, sugar, and unhealthy fats, and low in fiber, contribute to weight gain