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Conclusion Glucagon-like peptide-1 receptor agonists (GLP-1RAs) represent a promising therapeutic avenue for heart failure with preserved ejection fraction (HFpEF)

[DOI] [PubMed] [Google Scholar] 73.Tuttle KR, et al

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Retatrutide is a single peptide with agonist activity at the glucose-dependent insulinotropic polypeptide (GIP), glucagon-like peptide (GLP)-1, and glucagon receptors

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Safety data also plays a role in guiding these practices