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The cells were exposed to a range of treatments: TGF-1 (10 ng/ml, R&D Systems Inc., Minneapolis, USA), IL-1 (10 ng/ml, R&D Systems Inc., Minneapolis, USA), MCC950 (10 M, Selleck, Houston, TX, USA), 3PO (10 or 30 M, Selleck, Houston, TX, USA), liraglutide (10, 100 or 1000 nM, Selleck, Houston, TX, USA), and sodium L-lactate (20 mM, Sigma-Aldrich, St
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Because lifestyle modifications alone are often inadequate, two or more agents are usually required to attain adequate glycemic control