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Patients often experience enhanced tolerability through the gradual therapeutic introduction, with a notably reduced incidence of gastrointestinal side effects

These bacteria, residing in a glycan-rich environment, are able to digest mucus through mucus-degrading enzymes, such as sulphatase, glycosidase, neuraminidase, galactosidase, cysteine protease, and sialidases that cleave the mucus, producing short-chain fatty acids (SCFAs)

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compared pregnancy outcomes in women exposed to GLP1-RAs in early pregnancy (n = 168), combining all GLP1-RA drugs despite the differences in effectiveness, either for diabetes or obesity treatment with those in two reference groups: (i) women with diabetes exposed to at least one non-GLP1-RA anti-diabetic drug during the first trimester and (ii) a reference group of overweight/obese women without diabetes, between 2009 and 2022 (Dao et al