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However, subsequent clinical trials reported high rates of nausea and vomiting, leading to the perception that PYY-based therapies were intrinsically intolerable

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Inflammation is also known to be a key factor in the development of AS: the aggregation of white blood cells, mainly macrophages, is a significant feature of AS from its initial to its late stage (116)

[DOI] [PMC free article] [PubMed] [Google Scholar] 134.Larsen PJ, Tang-Christensen M, Holst JJ, Orskov C
Diabetes Care 47 , 17181730 (2024)

doi: 10.1038/nrendo.2015.231
