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Description
In both trials, weight reduction was assessed after 72 weeks of treatment (at least 52 weeks at maintenance dose)
The GRADE evaluation of the evidence retrieved for the primary endpoint (reduction of knee pain, Supplementary Table 3) was rated as moderate for semaglutide and low for liraglutide (Supplementary Table 6)
But, as for humans, so for reptiles: beauty is in the eye of the beholder
The condition is strongly linked to metabolic issues, as an estimated 35% to 80% of patients experience insulin resistance
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Lonneman DJ Jr, Rey JA, McKee BD
