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Figure 2 Bidirectional interactions between gut microbiota and GLP-1 receptor agonists in metabolic regulation

Understanding this distinction is important when considering reports of period changes in women taking GLP-1 medications

ILC3s constitute a unique subgroup of ILCs defined by their presentation of the retinoid orphan receptor gamma t (RORt) and their capacity to secrete type 17 cytokines, including IL-17 and IL-22 [181, 182]

The GLP-1R is colored grey

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In vital metabolic tissues such as skeletal muscle, leptin is essential for preserving glucose balance by improving glucose absorption, glycogen formation and the oxidation of glucose and fatty acids [126]