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Description
Mayo Clinic Proceedings 9814581468
These molecules influence: GLP-1 and PYY secretion insulin sensitivity mitochondrial energy pathways fat oxidation inflammation modulation appetite and metabolic rhythm Scientific Reference 3: Koh et al., Cell (2016) This high-impact review explains SCFAs mechanistic roles in host physiology: signalling through receptors (e.g., FFAR2/FFAR3), epigenetic modulation, immunegut interactions, and metabolic regulation

Adipose tissue, particularly visceral fat, is metabolically active and secretes pro-inflammatory adipokines

These symptoms are often dose-dependent, with higher doses leading to more severe side effects

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GLP-1 receptors are also expressed in blood vessels, suggesting effects on vascular function and circulation
